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The long-standing myth surrounding Brahe's final days is that he died of a bladder infection; because it would have been impolite for him to leave a banquet he was attending before it was over, even to relieve himself, he stayed and was said to have strained himself, dying 11 days later. Subsequent analysis of hair from his remains, however, detected massive quantities of mercury.
Since like most scientific men of his day, Tycho was also a keen alchemist, it's unlikely that he would have taken such massive quantities of it himself, even though mercuric chloride was a staple ingredient in much of that era's medicine. Modern fingers tend to point to poisoning, and to Kepler as the poisoner; Kepler had the means, motive, opportunity, and not only stole much of Tycho's research following his mentor's death but worked at submerging Tycho's reputation for generations to come as well.
Tycho Brahe is buried in the Church of Our Lady in front of Týn, in Prague, near the Old Town Square.
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